Julian Hartley has been appointed permanent chief executive of University Hospital of South Manchester foundation trust.
He joined on an interim basis from Blackpool, Fylde and Wyre Hospitals foundation trust in March after Peter Morris left to become interim chief at Barts and the London trust.
Mr Hartley said: “UHSM is a leading teaching hospital. It is recognised as a centre of clinical excellence, with a reputation for delivering high quality pioneering research.”
South Manchester chair Felicity Goodey added: “Julian has an excellent track record of delivering high quality healthcare.
“He also has a growing national reputation for his work pioneering leadership skills within the NHS.”
Mr Morris, who had been chief at the trust since 2002, moved to Barts after the resignation of Julian Nettel amid concerns about the trust’s finances and ability to achieve foundation status.
Blackpool deputy chief executive Aidan Kehoe remains its interim chief pending an appointments process.