Health secretary Andy Burnham has asked regulators to investigate Tameside Hospital Foundation Trust after local MPs demanded management changes.

A Department of Health spokeswoman said the health secretary had been in contact with the foundation trust regulator Monitor “to ask for urgent assurances about the trust’s performance following concern from local MPs”.

We believe it is time to say, ‘enough is enough’

The four Labour MPs for Tameside and Glossop – Andrew Gwynne, David Heyes, James Purnell and Tom Levitt – issued a strongly worded joint statement this week, calling for a “fresh start”.

It is the latest move in an ongoing row about standards at Tameside General Hospital. The hospital had a poor showing in the Dr Foster Good Hospital Guide and an unannounced Care Quality Commission inspection in December found evidence the trust breached guidelines on the prevention of healthcare-associated infections.

In the statement, the MPs said: “We believe it is time to say, ‘enough is enough’. We have been reluctant to call for fundamental changes in the running of the hospital. But we now believe it is a necessary first step if the hospital is to get the fresh start that the people of Tameside and Glossop deserve.”

A Monitor spokeswoman said the regulator was working with the Care Quality Commission to determine if there was any basis to take regulatory action.

However, Christine Green, the trust’s chief executive for the past 10 years, insisted she would remain in post.

“I do not believe the world is as the MPs describe. I have a long list of the improvements and achievements the hospital has made,” she told the Manchester Evening News, which is also campaigning for her removal.

A trust spokesman said: “We are unaware of any formal request from any MP in relation to changes in senior management.”