Collection of blood from the umbilical cords of newborns is to be regulated by the Human Tissue Authority for the first time.
From 5 July, cord blood will only be able to be collected by people with specialist training on premises that meet certain standards.
HTA chief executive Adrian McNeil said the rules would ban fathers from being involved in the procedure. He said: "The worry is that if inexperienced people are involved, this will not be done at the right time and in the right way. The result is that the best samples may not be collected."
Collection of cord blood has risen because of its potential medical uses, including treatment of leukaemia.
For more details, visit www.hta.gov.uk