Chair, Royal College of GPs (2010 ranking: 11)

The HSJ100’s second most powerful working GP has deployed her compelling and emotive style to enormous effect, and elicited strong reactions - positive and negative. Dr Gerada is using her tenure to address difficult issues such as addiction and mental health. She will also continue to energetically defend medical generalism and remains an enthusiastic advocate for telehealth.

But by far her greatest impact will be her continued opposition to much government policy. Her critiques are powerful and those listening know Dr Gerada commands a lot of professional support.

The downside, part of the reason for her slide down the list, is that her messages can be broad-brush and sometimes contradictory. It means that - while able to give Andrew Lansley a splitting headache and block his path - Dr Gerada is less listened to on policy specifics.