The winner of the competition to create a new £50m children's hospital for Guy's and St Thomas' Hospital trust had a brief to design 'a hospital that does not feel like a hospital'. Children, parents and local people were invited to have a say in selecting the shortlisted designs.

The winning entry, a six-storey glass-fronted building, claims to capitalise on the dramatic Thamesside setting with a 'feeling for space and nature'.

Clinical director of paediatrics Dr Ted Baker said he had wanted the plans to include 'a fun space for children of all ages'.

The winning design (top) is by Sir Michael Hopkins, whose recent credits include Portcullis House - the new Parliament building in London.

Other designs on the shortlist in the competition, run by the Royal Institute of British Architects, included: a tinted glass box covered in zebraprint designs, produced by Alsop and Stormer (below left); a high-tech building with a viewing tower from Anshen Dyer with Ove Arup and Partners (left); a building with curved corridors and a roof garden from KPF Canon with Mott MacDonald (bottom right), and a terracotta-clad building with recessed windows overlooking Lambeth Palace Gardens, produced by Skidmore Owings and Merrill (bottom left).

The hospital will have 120 inpatient beds, a day-case unit and 20 paediatric intensive-care beds. The project will be funded by the trustees of the charitable fund for St Thomas' Hospital as part of a£100m investment strategy for the trust agreed by the government.