Topical application of eye drops containings and restore damaged vision, according to researchers from Rome University. They gave eye drops containing 10microg of murine nerve growth factor to 12 patients 10 times a day for two days, then six times a day until the ulcers had healed. Treatment was continued for two weeks after healing.
Healing began within two to 14 days of treatment starting and all patients had complete resolution of their ulcers after six weeks. The study is the first to show a promising medical treatment for the disorder.
Lambiase A et al. Topical treatment with nerve growth factor for corneal neuropathic ulcers. New Engl J Med 1998; 338 (17): 1174-80.