Stoke Mandeville Hospital has made 'substantial progress' to prevent and manage healthcare-associated infections, the Healthcare Commission has said.

Last year, the commission found that 'serious failings' by managers had led to two separate outbreaks of Clostridium difficile between October 2003 and June 2005 in which 334 patients contracted the infection and at least 33 people died.

But further progress was still needed, said the commission, including basic hand hygiene by doctors, increased staffing levels, and the clinical management of patients with C difficile.

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